博文

目前显示的是 五月, 2019的博文

A brief talk on the cancer antigen 19 9

Cancer antigens generally refer to antigenic substances that are newly or overexpressed during tumorigenesis and development. The possible mechanisms by which the body produces cancer antigens  are: 1 gene mutation; 2 cells that are not expressed in the cell carcinogenesis are activated; 3 abnormalities occur in a certain writing process of the antigen synthesis process (such as abnormal glycosylation results in the production of specific carrier protein  degradation products) Abnormal, ectopic expression of 4 embryonic antigens or differentiation antigens; 5 overexpression of certain gene products, especially signal transduction molecules; 6 expression of exogenous genes (such as viral genes). Tumor-targeted clinical treatment for tumor-specific cancer antigens is a therapeutic approach with broad application prospects. Obtaining immune cells capable of highly recognizing cancer antigens, using genetic engineering methods and TCR-T and CAR-T are the most commonly used methods for

A brief talk on the cowpox

Cowpox is an infectious disease occurring in cattle. It is an acute infection caused by smallpox virus. Its symptoms are usually local ulcers in the breast of cows. The virus can be transmitted to humans through contact, mostly in milkers, slaughterhouse workers, patients with skin papules, these papules slowly develop into blisters, pustules, but also some other symptoms. Historically, most cases of the disease occurred in Europe, especially in the United Kingdom. The virus can be found in cattle, cats and voles. Human cases are rare and the incubation period is 9 to 10 days, but for patients with immune system deficiencies, cowpox virus  infection is lethal enough. According to WHO's current report, the disease is now disappearing globally. Cowpox virus is a virus that can cause mild varicella in cattle. If people are infected with the virus, they will only produce slight discomfort and resistance to cowpox virus. Since cowpox virus has the same antigenic properties as smallp