博文

目前显示的是 四月, 2019的博文

An introduction to Adjuvant Selection

Adjuvant Selection  and Adjuvant Optimization  services are widely used in the search for molecular genetic markers and vaccine markers, including bacterial vaccines , DNA vaccines , cancer vaccines , etc., MAS breeding methods MAS and QTL The application of the principles and methods of modern quantitative genetics in pig breeding has achieved great success, and it is still an indispensable selection method for some quantitative traits with high heritability and continuous normal distribution. However, for low genetic traits, such as sow litter size, the selection response was not ideal. Therefore, animal genetic breeders can find the genetic difference of traits or the genetic markers linked with quantitative traits at the molecular genetic level, so as to realize the true genotype selection. The rapid development of molecular genetics and determination technology has greatly promoted the in-depth study of livestock genome analysis. Can know the genetic material from the nucleic ac

Vaccine adjuvant and its application

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Vaccine adjuvant What is an  adjuvant vaccine ?   Adjuvant, also known as immunomodulator or immunopotentiator, originated from the Latin word "Adjuvare" and is auxiliary or enhanced. An adjuvant is an additive of a vaccine. When it is injected into the body prior to the antigen or mixed with the antigen, it can enhance the body's immune response to the antigen or change the type of immune response. It is a non-specific immunopotentiator and has no antigen itself. An ideal adjuvant not only enhances the immune response, but also provides the body with optimal protective immunity. Purpose of application Studies have shown that   the interaction of vaccine adjuvants with the body mainly include immunomodulation, cytotoxic T lymphocyte induction, antigen presentation, antigen targeting and storage. Through the above several methods, the purpose of use is achieved as follows: (1) Enhancing the immunogenicity, immune response rate and tolerance of purified or re

Development and clinical research of vaccine adjuv

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Vaccine adjuvant What is the adjuvant for the vaccine ? A vaccine adjuvant (Adjuvant) is a substance that can non-specifically change or enhance the body's specific immune response to an antigen and play a supporting role. Adjuvant can induce long-term, high-efficiency specific immune response, improve the body's protective ability, and at the same time reduce the amount of immune substances and reduce the cost of vaccine production. The development direction of vaccine adjuvant Although the knowledge of immunology has made great progress in the past decade, it is surprising that aluminum-based complexes are mainly used as the main adjuvant in human vaccines. This situation will not change in the next few decades for the already established high-efficiency vaccine. However, the introduction of new recombinant subunits and synthetic antigens into HIV, hepatitis C virus, malaria and other serious diseases, as well as the development of therapeutic vaccines for chronic d